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    Home»Columns»Colorectal cancer Is now the leading cause of cancer death for those under 50 in the U.S. — you can’t afford to miss the warning signs
    Columns

    Colorectal cancer Is now the leading cause of cancer death for those under 50 in the U.S. — you can’t afford to miss the warning signs

    By Amy VelozMarch 19, 2026No Comments3 Mins Read
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    By Dr. John Rhodes
    President and CEO
    Optum Nevada

    Colorectal cancer is now the leading cause of cancer death among people younger than 50 in the United States, according to a 2026 study by the American Cancer Society published in the Journal of the American Medical Association.[1] At the same time, colorectal cancer diagnosis rates for those younger than 50 have risen by 2.9% per year from 2013 to 2022.[2]

    As a physician practicing in Nevada for many years, I’ve watched colorectal cancer shift from a condition most patients associated with retirement age to one I’m now discussing with people in their 30s and 40s. Nationally, the American Cancer Society projects that in 2026, there will be nearly 109,000 cases of colon cancer, split about equally between men and women, and nearly 50,000 new cases of rectal cancer, with 28,750 in men and 21,240 in women.[3]

    These trends are not abstract. They show up in exam rooms as younger patients presenting with symptoms they often dismiss or delay addressing. Common warning signs can include changes in bowel habits, blood in or on the stool, ongoing abdominal discomfort and unexplained weight loss.[4]

    Part of the danger is that early colorectal cancer can be subtle. Some cases of polyps or colorectal cancer are not associated with symptoms, especially at first.[5] The tragedy is that colorectal cancer is one of the few cancers where screening can do more than detect disease early — it can prevent cancer altogether by identifying and removing precancerous polyps, before they become malignant.[6]

    Public awareness tends to spike when public figures are affected by cancer. Coverage involving actors such as James Van Der Beek, who was 48 when he passed recently from colorectal cancer, has helped bring attention to the reality that this disease can affect younger people. Those moments can prompt important conversations, but colorectal cancer is not a celebrity issue. It’s a community issue, and it’s affecting families across Nevada.

    There is also encouraging news here. When colorectal cancer is detected at the localized stage, the five-year survival rate exceeds 90%.[7] Outcomes worsen dramatically once the disease spreads, underscoring why timing matters.[8]

    According to America’s Health Rankings, just over 63% of Nevada adults ages 45 to 75 are up to date on one or more recommended colorectal cancer screening tests.[9]

    Screening saves lives, and it saves health care dollars by preventing advanced disease. Yet too many younger adults assume screening isn’t relevant to them, and too many older adults delay testing because they feel well. Both assumptions can be costly. The American Cancer Society and other medical organizations recommend that average-risk adults begin regular screening at age 45, and earlier for those with family history or other risk factors.[10]

    Colorectal cancer is becoming more common among younger people, but it remains one of the most preventable and treatable cancers when we act early. Awareness is the first step. Screening is the next. Your life may depend on both. 


    [1]Colorectal cancer now top cancer killer | American Cancer Society
    [2]https://www.cancer.org/cancer/types/colon-rectal-cancer/about/key-statistics.html
    [3] Key Statistics for Colorectal Cancer | American Cancer Society
    [4]Symptoms of Colorectal Cancer | CDC
    [5]Symptoms of Colorectal Cancer | CDC[6]Reducing Risk for Colorectal Cancer | Colorectal Cancer | CDC
    [7]Survival rates for colorectal cancer | CDC
    [8]Survival rates for colorectal cancer | CDC
    [9]https://www.americashealthrankings.org/explore/measures/colorectal_cancer_screening/NV#measure-trend-summary
    [10]American Cancer Society Guideline for Colorectal Cancer Screening | American Cancer Society

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    Amy Veloz

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